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News from AAO



Sulfur hexafluoride tamponade may reduce DMEK graft detachment
This retrospective single-center study compared 1-year outcomes following Descemet membrane endothelial keratoplasty (DMEK) with either conventional anterior chamber air tamponade or 20% sulfur hexafluoride gas (SF620%) tamponade. Among 854 consecutive DMEK cases, 105 were treated with SF620% and 749 with 100% air. Eyes that received SF620% showed a significantly lower rate of graft detachment requiring rebubbling (P<0.001). There were no statistically significant differences in postoperative IOP, BCVA, endothelial cell density or central corneal thickness between groups at any follow-up time point. Rates of intra- and postoperative complications, including graft failure and rejection, were also similar. These results suggest SF620% tamponade may be a safe and effective alternative to air. British Journal of Ophthalmology, July 2017

Immunosuppressive therapy linked to better outcomes in retinal vasculitis
Investigators retrospectively assessed rates of vision loss and ocular complications in a cohort of 96 patients with retinal vasculitis (RV). Over a median follow-up of 44 months, the rate of vision loss to 20/50 or worse was 0.13/eye-year (EY), and to 20/200 or worse was 0.06/EY—rates similar to those previously reported for noninfectious uveitides. Common complications included cataract (0.31/EY), epiretinal membrane (0.16/EY) and recurrent macular edema (0.09/EY). Notably, patients who received immunosuppressive therapy had a significantly lower risk of vision loss (OR 0.79, P=0.01). Those with relapsing disease had approximately twice the risk of vision loss, but this finding was not statistically significant due to the small sample size. American Journal of Ophthalmology, July 2017




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